HitPredict

Interactor 1: MATN2 (O00339)
Matrilin-2
Gene: MATN2

Interactor 2: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~VWA
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 956 Hs			1 399
+	Hs
		126325 MATN2_HUMAN (1-956): 0: 666: 100.00		IGHG2_HUMAN (1-399): 3.98e-103: 312: 90.48
+	Hs
		126326 MATN2_HUMAN (1-956): 0: 666: 100.00		IGHG3_HUMAN (1-399): 7.71e-97: 298: 83.86
+	Hs
		126328 MATN2_HUMAN (1-956): 0: 666: 100.00		IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85
+	Hs
		126329 MATN2_HUMAN (1-956): 0: 666: 100.00		IGHA2_HUMAN (1-374): 4.63e-60: 201: 28.72
+	Hs
		126327 MATN2_HUMAN (1-956): 0: 666: 100.00		IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90
+	Hs
		126397 MATN2_HUMAN (1-956): 0: 666: 100.00		PXDN_HUMAN (2-154): 1.82e-11: 68.1: 12.26
+	Hs
		82353 MATN2_HUMAN (1-956): 0: 666: 100.00		IGLL5_HUMAN (2-103): 7.8e-12: 66.3: 31.43
+	Hs
		126323 MATN2_HUMAN (1-956): 0: 666: 100.00		IGKC_HUMAN (229-321): 1.52e-09: 57: 29.47
+	Hs
		353697 LTBP4_HUMAN (172-661): 2.1e-26: 119: 20.14		IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00
+	Hs
		403550 COEA1_HUMAN (649-949): 5.63e-41: 166: 23.86		DQB2_HUMAN (169-332): 9.68e-45: 157: 23.53
+	Hs
		980481 NOTC2_HUMAN (405-724): 5.84e-21: 101: 17.17		PXDN_HUMAN (2-154): 1.82e-11: 68.1: 12.26