Interactor 1: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Interactor 2: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 23602568
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~fn3, I-set~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0106310 - protein serine kinase activity
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 34350
Hs

1 601
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024