Interactor 1: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3
Interactor 2: AFG2B (Q9BVQ7)
ATPase family gene 2 protein homolog B (EC 3.6.4.10) (AFG2 AAA ATPase homolog B) (Ribosome biogenesis protein SPATA5L1) (Spermatogenesis-associated protein 5-like protein 1)
Gene: AFG2B
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned3799 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~AAA, AAA~AAA_lid_3, AAA_lid_3~AAA_lid_3, AAA~Prot_ATP_ID_OB_C |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025