HitPredict

Interactor 1: TR10A (O00220)
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)
Gene: TNFRSF10A

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006915 - apoptotic process GO:0007165 - signal transduction GO:0043065 - positive regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 468 Hs			1 196
+	Hs
		127664 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		127661 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		127629 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57
+	Hs
		127666 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53
+	Hs
		127624 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16
+	Hs
		127658 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54
+	Hs
		127660 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		127631 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOQ_HUMAN (2-195): 6.74e-68: 207: 51.74
+	Hs
		126351 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98
+	Hs
		163273 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		163270 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		163271 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00
+	Hs
		163230 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57
+	Hs
		163279 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53
+	Hs
		163224 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16
+	Hs
		163267 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54
+	Hs
		163268 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		163236 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOQ_HUMAN (2-195): 6.74e-68: 207: 51.74
+	Hs
		622565 TNR1A_HUMAN (124-448): 4.99e-61: 207: 18.94		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		466103 TNR1A_HUMAN (124-448): 4.99e-61: 207: 18.94		RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16