HitPredict

Interactor 1: TR10A (O00220)
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)
Gene: TNFRSF10A

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 468 Hs			1 618
+	Hs
		127629 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		127658 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		127660 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		127666 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOG_HUMAN (3-170): 1.69e-74: 238: 27.47
+	Hs
		127664 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		163230 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		163267 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22
+	Hs
		163268 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54
+	Hs
		163279 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOG_HUMAN (3-170): 1.69e-74: 238: 27.47
+	Hs
		163273 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RAC1_HUMAN (3-181): 3.96e-74: 237: 26.43
+	Hs
		127663 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		127661 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		127729 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOF_HUMAN (2-167): 3.39e-11: 65.1: 26.67
+	Hs
		127624 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		126351 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		127631 TR10A_HUMAN (1-468): 6.32e-162: 467: 100.00		RHOQ_HUMAN (5-169): 2.03e-10: 62.8: 26.26
+	Hs
		163271 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOB_HUMAN (6-168): 4.59e-13: 70.1: 29.38
+	Hs
		163270 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOA_HUMAN (6-168): 1.75e-11: 65.5: 28.25
+	Hs
		163224 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOC_HUMAN (6-168): 3.88e-11: 64.3: 28.25
+	Hs
		163236 TR10B_HUMAN (60-466): 3.3e-109: 332: 51.91		RHOQ_HUMAN (5-169): 2.03e-10: 62.8: 26.26