HitPredict

Interactor 1: SAP18 (O00422)
Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)
Gene: SAP18

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.908

The method score is based on:

Property	Details
Experiments	22388736, 33961781, 16537548, 12665594
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RRM_1~SAP18
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 5 others more... GO:0008380 - RNA splicing GO:0016607 - nuclear speck GO:0043065 - positive regulation of apoptotic process GO:0048025 - negative regulation of mRNA splicing, via spliceosome GO:0061574 - ASAP complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	153
Hs

1	305

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024