HitPredict

Interactor 1: PSD12 (O00232)
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
Gene: PSMD12

Interactor 2: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 19615732, 28292943, 35271311, 40437099
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MitMem_reg~PCI, JAB~RPN5_C, MitMem_reg~RPN5_C
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 456
Hs

1 324
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Service provided by Combinatics, Japan

Last updated: 11Aug2025