Interactor 1: LRC8A (Q80WG5)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (Protein ebouriffe) (ebo) (Swelling protein 1)
Gene: Lrrc8a
Interactor 2: LRC8C (Q8R502)
Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)
Gene: Lrrc8c
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.34 | 1.00 | 0.584 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29769723 |
| Identification Methods | 3D electron microscopy |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_1~LRR_8, LRR_8~LRR_8, Pannexin_like~Pannexin_like |
| Common GO terms | GO:0005225 - volume-sensitive anion channel activity GO:0005886 - plasma membrane GO:0015734 - taurine transmembrane transport GO:0015810 - aspartate transmembrane transport GO:0034214 - protein hexamerization and 3 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025