HitPredict

Interactor 1: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Interactor 2: ISY1 (Q9ULR0)
Pre-mRNA-splicing factor ISY1 homolog
Gene: ISY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 315 Hs			1 285
+	Hs
		209495 PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15		ISY1_HUMAN (1-285): 3.91e-120: 347: 100.00
+	Hs
		236263 PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40		ISY1_HUMAN (1-285): 3.91e-120: 347: 100.00
+	Hs
		1288383 SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47		ISY1_HUMAN (1-285): 3.91e-120: 347: 100.00
+	Sp
		195151 PRP17_SCHPO (224-306): 1.02e-11: 67.5: 16.47		ISY1_SCHPO (23-185): 2.51e-52: 172: 36.75