HitPredict

Interactor 1: NRAP (Q80XB4)
Nebulin-related-anchoring protein (N-RAP)
Gene: NRAP

Interactor 2: FLNC (Q8VHX6)
Filamin-C (FLN-C) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	12692149
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CH~LIM
Common GO terms	GO:0003779 - actin binding GO:0030018 - Z disc GO:0051015 - actin filament binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1728 Mm			1 2726
+	Mm
		313239 NRAP_MOUSE (1-1728): 0: 1950: 100.00		ACTN3_MOUSE (17-435): 1.48e-119: 405: 24.66
+	Hs
		773758 NRAP_HUMAN (1-1728): 0: 1895: 86.14		ACTN2_HUMAN (2-435): 3.79e-119: 403: 24.40
+	Hs
		637778 LIMA1_HUMAN (4-78): 1.3e-13: 78.1: 26.67		FLNA_HUMAN (148-2726): 0: 1470: 35.39
+	Hs
		278176 LIMA1_HUMAN (4-78): 1.3e-13: 78.1: 26.67		FLNB_HUMAN (147-2726): 0: 1426: 35.51
+	Hs
		1028906 LIMA1_HUMAN (4-78): 1.3e-13: 78.1: 26.67		SPTB2_HUMAN (4-440): 5.05e-117: 418: 24.72
+	Hs
		302163 NEBL_HUMAN (2-263): 6.3e-19: 95.8: 14.53		ACTN3_HUMAN (24-387): 4.81e-118: 400: 27.30
+	Hs
		73650 NEBL_HUMAN (2-263): 6.3e-19: 95.8: 14.53		B2R8Y4_HUMAN (24-387): 7.72e-118: 400: 27.30
+	Hs
		1028804 MICA3_HUMAN (4-58): 7.22e-12: 73.1: 29.83		SPTB2_HUMAN (4-440): 5.05e-117: 418: 24.72
+	Hs
		773715 CSRP3_HUMAN (5-159): 6.09e-14: 74.3: 17.34		ACTN2_HUMAN (2-435): 3.79e-119: 403: 24.40
+	Hs
		555601 CSRP1_HUMAN (4-142): 3.48e-13: 72: 16.35		ACTN1_HUMAN (6-438): 3.2e-119: 403: 24.56
+	Dm
		612386 LASP1_DROME (677-801): 1.47e-24: 113: 20.74		ACTN_DROME (1-316): 1.65e-101: 352: 27.89
+	Hs
		224823 LIMA1_HUMAN (4-78): 1.3e-13: 78.1: 26.67		ACTN4_HUMAN (17-378): 6.86e-110: 376: 27.70