HitPredict

Interactor 1: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Interactor 2: EHMT2 (Q9Z148)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a)
Gene: EHMT2

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23892456
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 305 Mm			1 1263
+	Mm
		1204123 NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00		EHMT1_MOUSE (131-1259): 0: 639: 47.10
+	Hs
		725321 TLX1_HUMAN (29-215): 7.18e-34: 128: 22.80		EHMT1_HUMAN (2-1259): 0: 640: 44.84
+	Hs
		685351 PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82		EHMT1_HUMAN (2-1259): 0: 640: 44.84
+	Hs
		226601 TLX2_HUMAN (60-158): 7.64e-27: 108: 30.39		EHMT1_HUMAN (2-1259): 0: 640: 44.84
+	Hs
		225114 TLX3_HUMAN (89-153): 9.36e-09: 57.4: 43.08		EHMT1_HUMAN (2-1259): 0: 640: 44.84
+	Hs
		177178 HXA7_HUMAN (24-166): 3.3e-31: 118: 18.88		ANR28_HUMAN (515-951): 4.07e-70: 258: 17.18
+	Hs
		332384 HXB2_HUMAN (4-305): 1.46e-31: 122: 17.88		TNKS1_HUMAN (610-1172): 2.58e-63: 238: 15.66
+	Hs
		725305 TLX1_HUMAN (29-215): 7.18e-34: 128: 22.80		EHMT2_HUMAN (18-823): 1.1e-38: 159: 11.31
+	Hs
		604777 HXB8_HUMAN (5-164): 1.44e-31: 119: 22.50		ANKH1_HUMAN (563-834): 5.38e-41: 167: 18.48
+	Hs
		724981 HXA7_HUMAN (24-166): 3.3e-31: 118: 18.88		ANKH1_HUMAN (563-834): 5.38e-41: 167: 18.48
+	Hs
		685313 PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82		EHMT2_HUMAN (18-823): 1.1e-38: 159: 11.31
+	Hs
		226586 TLX2_HUMAN (60-158): 7.64e-27: 108: 30.39		EHMT2_HUMAN (18-823): 1.1e-38: 159: 11.31
+	Hs
		574035 HXB2_HUMAN (4-305): 1.46e-31: 122: 17.88		TNKS2_HUMAN (808-1073): 1.06e-33: 143: 21.53
+	Hs
		225080 TLX3_HUMAN (89-153): 9.36e-09: 57.4: 43.08		EHMT2_HUMAN (18-823): 1.1e-38: 159: 11.31