HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	11894095
Identification Methods	coimmunoprecipitation, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 665 Hs			1 368
+	Hs
		1285181 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		1285180 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Mm
		1143925 SH3K1_MOUSE (1-665): 4.53e-118: 370: 87.59		SH3G2_MOUSE (1-368): 8.98e-84: 260: 69.02
+	Hs
		1285230 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SHLB1_HUMAN (10-363): 3.1e-69: 223: 25.28
+	Hs
		1285199 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		SHLB2_HUMAN (10-363): 1.2e-58: 196: 22.39
+	Hs
		1307444 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		1089305 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		RHG44_HUMAN (6-251): 8.5e-47: 172: 22.22
+	Hs
		1148382 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		RHG17_HUMAN (6-267): 6.29e-35: 137: 21.83
+	Hs
		1285232 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		3BP1_HUMAN (6-260): 2.89e-33: 132: 18.62
+	Hs
		1089312 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		RHG44_HUMAN (6-251): 8.5e-47: 172: 22.22
+	Hs
		1052363 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		924773 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		1148393 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		RHG17_HUMAN (6-267): 6.29e-35: 137: 21.83
+	Hs
		1377711 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		3BP1_HUMAN (6-260): 2.89e-33: 132: 18.62
+	Mm
		1141153 SH3K1_MOUSE (1-665): 4.53e-118: 370: 87.59		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924988 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Mm
		1141167 CD2AP_MOUSE (1-663): 7.79e-83: 276: 31.53		GRB2_MOUSE (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		1052222 SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		1136530 SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72		SH3R3_HUMAN (305-362): 1.03e-11: 68.3: 43.55
+	Hs
		924630 SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38