HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 665 Hs			1 669
+	Hs
		1078886 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		61871 SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00		CC88B_HUMAN (60-668): 4.55e-16: 84.7: 12.48
+	Hs
		1051533 CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		997493 Q08AM8_HUMAN (1-597): 1.8e-44: 171: 16.51		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1256102 SH3R2_HUMAN (1-597): 1.19e-43: 169: 16.35		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		924829 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1167823 DNMBP_HUMAN (104-607): 3.03e-16: 85.1: 15.82		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		209152 NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1078919 ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		1078828 ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		924566 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		924736 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		728465 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53
+	Hs
		924919 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		EP15R_HUMAN (483-668): 6.69e-11: 67.8: 12.90
+	Hs
		924586 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		725134 GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		1349279 ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30		EP15R_HUMAN (483-668): 6.69e-11: 67.8: 12.90
+	Hs
		61738 A6H8W8_HUMAN (30-455): 4.81e-26: 116: 15.30		EP15R_HUMAN (483-668): 6.69e-11: 67.8: 12.90
+	Hs
		1078923 ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01		EP15R_HUMAN (483-668): 6.69e-11: 67.8: 12.90
+	Hs
		148836 ARHG6_HUMAN (218-345): 4.37e-16: 84.3: 24.81		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36