Interactor 1: SIR1 (Q96EB6)
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
Gene: SIRT1

Interactor 2: IMP2L (Q96T52)
Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein)
Gene: IMMP2L

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.51 0.60 0.554

The method score is based on:

Property Details
Experiments 31617661
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006974 - DNA damage response
GO:0007283 - spermatogenesis
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 747
Hs

1 175
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024