HitPredict

Interactor 1: CHFR (Q96EP1)
E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR)
Gene: CHFR

Interactor 2: CHFR (Q96EP1)
E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR)
Gene: CHFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 11912157, 11807090, 12121644, 18172500
Identification Methods enzymatic study, x-ray crystallography
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FHA~FHA, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000166 - nucleotide binding
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
and 10 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 664
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024