HitPredict

Interactor 1: CYFP2 (Q96F07)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: CYFIP2

Interactor 2: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17101133
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Abi_HHR~FragX_IP
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0031209 - SCAR complex
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 366
+	Mm
		913886 CYFP2_MOUSE (1-1278): 0: 2126: 97.97		ABI2_MOUSE (1-363): 1.65e-86: 270: 34.40
+	Hs
		1290817 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		PACN2_HUMAN (17-363): 1.11e-44: 162: 14.29
+	Hs
		1290802 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		PACN1_HUMAN (11-363): 5.47e-37: 140: 12.67
+	Mm
		1131060 CYFP2_MOUSE (1-1278): 0: 2126: 97.97		SRC8_MOUSE (40-363): 2.92e-41: 153: 13.71
+	Hs
		1290809 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18
+	Hs
		1224632 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49
+	Hs
		924782 CYFP2_HUMAN (1-1278): 0: 2164: 100.00		GRB2_HUMAN (312-363): 4.03e-14: 72.7: 28.30
+	Mm
		1131118 CYFP2_MOUSE (1-1278): 0: 2126: 97.97		ABI1_MOUSE (272-363): 1.7e-21: 97.4: 44.57
+	Hs
		1184662 CYFP1_HUMAN (1-1277): 0: 2040: 85.92		ABI2_HUMAN (109-363): 4.36e-25: 108: 23.18
+	Hs
		1184628 CYFP1_HUMAN (1-1277): 0: 2040: 85.92		ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49
+	Mm
		1186395 CYFP1_MOUSE (1-1277): 0: 2032: 85.68		ABI1_MOUSE (272-363): 1.7e-21: 97.4: 44.57
+	Dm
		1365310 CYFIP_DROME (1-1277): 0: 1898: 64.75		Q9Y0S9_DROME (260-364): 1.16e-20: 94.7: 38.32
+	Dd
		1122367 PIRA_DICDI (7-1249): 0: 1445: 36.98		ABIA_DICDI (3-321): 6.97e-30: 119: 19.32