HitPredict

Interactor 1: PGBD1 (Q96JS3)
PiggyBac transposable element-derived protein 1 (Cerebral protein 4)
Gene: PGBD1

Interactor 2: ZN446 (Q9NWS9)
Zinc finger protein 446 (Zinc finger protein with KRAB and SCAN domains 20)
Gene: ZNF446

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.972

Property	Details
Experiments	25416956, 32296183, 25910212, 28514442, 33961781, 31515488, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid bait and prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	SCAN~SCAN
Common GO terms	GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 809 Hs			1 450
+	Hs
		1281566 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZKSC4_HUMAN (11-449): 8.19e-125: 375: 23.51
+	Hs
		200841 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZSC12_HUMAN (19-450): 3.79e-95: 300: 16.85
+	Hs
		1078416 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZKSC8_HUMAN (188-421): 1.29e-86: 277: 16.92
+	Hs
		1295717 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZN232_HUMAN (15-417): 4.26e-84: 266: 25.81
+	Hs
		563729 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZKSC1_HUMAN (95-421): 2.39e-74: 244: 14.29
+	Hs
		154566 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZN213_HUMAN (369-450): 9.71e-34: 133: 32.18
+	Hs
		1295713 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZKSC3_HUMAN (142-329): 7.96e-30: 123: 6.79
+	Hs
		1252668 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZSC18_HUMAN (11-448): 2.7e-29: 121: 30.92
+	Hs
		1294643 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZN496_HUMAN (15-445): 5.55e-28: 118: 30.57
+	Hs
		1295711 PGBD1_HUMAN (1-809): 0: 758: 100.00		PGBD1_HUMAN (23-209): 3.3e-23: 104: 36.90
+	Hs
		1244157 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZN397_HUMAN (392-449): 6.34e-21: 97.4: 41.38
+	Hs
		1155990 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZSC25_HUMAN (112-302): 2.82e-20: 95.1: 5.61
+	Hs
		485189 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZSC22_HUMAN (52-167): 2.23e-13: 73.9: 8.55
+	Hs
		1295716 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZKSC7_HUMAN (55-142): 2.18e-10: 65: 5.68
+	Hs
		563839 PGBD1_HUMAN (1-809): 0: 758: 100.00		ZSC20_HUMAN (330-445): 2.1e-09: 62: 33.06
+	Hs
		1159590 PGBD2_HUMAN (332-805): 9.42e-153: 461: 53.65		PGBD1_HUMAN (23-209): 3.3e-23: 104: 36.90
+	Hs
		304679 ZN202_HUMAN (1-561): 3.03e-114: 363: 18.04		ZN250_HUMAN (17-299): 1.24e-50: 182: 8.14
+	Hs
		304683 ZN202_HUMAN (1-561): 3.03e-114: 363: 18.04		MZF1_HUMAN (252-450): 6.75e-46: 171: 21.34
+	Hs
		304680 ZN202_HUMAN (1-561): 3.03e-114: 363: 18.04		ZSC20_HUMAN (330-445): 2.1e-09: 62: 33.06
+	Hs
		3498 ZSC22_HUMAN (7-535): 3.46e-96: 310: 17.82		A0A0S2Z6X0_HUMAN (12-105): 1.81e-25: 103: 62.77