HitPredict

Interactor 1: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	18485199, 21518764
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	U-box~UQ_con
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 303
+	Hs
		1282365 UB2E3_HUMAN (1-201): 6.37e-85: 251: 79.71		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1357485 UB2D4_HUMAN (55-200): 9.37e-83: 243: 63.01		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		919907 UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		849489 UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		851908 UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		895956 UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		896567 UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	At
		715129 UBC8_ARATH (55-200): 9.15e-82: 241: 62.33		CHIP_ARATH (17-300): 4.28e-49: 166: 32.17
+	At
		715145 UBC9_ARATH (55-200): 8.45e-81: 238: 60.96		CHIP_ARATH (17-300): 4.28e-49: 166: 32.17
+	At
		715154 UBC10_ARATH (55-200): 9.43e-81: 238: 60.96		CHIP_ARATH (17-300): 4.28e-49: 166: 32.17
+	Ce
		105587 UBC2_CAEEL (55-200): 6.51e-82: 241: 65.07		G5ECY6_CAEEL (26-301): 5.16e-47: 160: 38.77
+	Ce
		105590 UBC13_CAEEL (57-200): 4.15e-70: 211: 49.31		G5ECY6_CAEEL (26-301): 5.16e-47: 160: 38.77
+	Zm
		31012 B4FC97_MAIZE (55-200): 8.66e-82: 241: 62.33		A0A1D6KE36_MAIZE (49-301): 5.96e-31: 123: 16.78
+	Zm
		14055 A0A1D6G0U5_MAIZE (56-165): 6.63e-52: 166: 69.09		A0A1D6LII0_MAIZE (24-300): 1.83e-48: 165: 34.04