Interactor 1: NR5A2 (O00482)
Nuclear receptor subfamily 5 group A member 2 (Alpha-1-fetoprotein transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Hepatocytic transcription factor) (Liver receptor homolog 1) (LRH-1)
Gene: NR5A2

Interactor 2: PROX1 (Q92786)
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)
Gene: PROX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.614

The method score is based on:

Property Details
Experiments 16488887, 15205472
Identification Methods pull down, two hybrid, anti bait coimmunoprecipitation, gal4 vp16 complementation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
and 8 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 541
Hs

1 737
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024