HitPredict

Interactor 1: RPB1 (P08775)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: Polr2a

Interactor 2: RECQ1 (Q9Z129)
ATP-dependent DNA helicase Q1 (EC 5.6.2.4) (DNA 3'-5' helicase Q1) (DNA-dependent ATPase Q1) (RecQ protein-like 1)
Gene: Recql

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37612308
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1970 Mm			1 648
+	Hs
		316254 RPB1_HUMAN (1-1611): 0: 1902: 100.00		RECQ5_HUMAN (73-487): 5.53e-174: 523: 36.76
+	Hs
		315132 RPB1_HUMAN (1-1611): 0: 1902: 100.00		RECQ4_HUMAN (76-453): 2.62e-124: 398: 31.37
+	Mm
		476226 RPB1_MOUSE (1-1611): 0: 1903: 100.00		DDX5_MOUSE (11-497): 1.04e-125: 386: 15.58
+	Hs
		667389 RPB1_HUMAN (1-1611): 0: 1902: 100.00		DDX17_HUMAN (11-447): 2.36e-124: 386: 15.35
+	Hs
		608455 RPB1_HUMAN (1-1611): 0: 1902: 100.00		DDX5_HUMAN (11-464): 1.54e-124: 383: 15.89
+	Hs
		193086 RPB1_HUMAN (1-1611): 0: 1902: 100.00		DDX3Y_HUMAN (18-448): 5.04e-112: 352: 12.85
+	Hs
		164989 RPC1_HUMAN (16-1487): 0: 1358: 33.36		RECQ4_HUMAN (76-453): 2.62e-124: 398: 31.37
+	Hs
		316238 RPA1_HUMAN (914-1476): 3.05e-39: 163: 16.25		RECQ5_HUMAN (73-487): 5.53e-174: 523: 36.76
+	Hs
		339952 RPA1_HUMAN (914-1476): 3.05e-39: 163: 16.25		RECQ1_HUMAN (1-648): 1.58e-150: 452: 85.05