HitPredict

Interactor 1: Q8IMX8 (Q8IMX8)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSm3

Interactor 2: Q9VJI7 (Q9VJI7)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSm7

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005688 - U6 snRNP GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome and 1 others more... GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Dm			1 110
+	Hs
		974292 LSM3_HUMAN (1-103): 4.33e-38: 125: 76.70		LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53
+	Hs
		574203 LSM3_HUMAN (1-103): 4.33e-38: 125: 76.70		RSMB_HUMAN (24-95): 2.41e-23: 91.5: 27.40
+	Hs
		974106 LSM3_HUMAN (1-103): 4.33e-38: 125: 76.70		RUXG_HUMAN (18-100): 2.35e-24: 89.6: 32.53
+	Dm
		1303485 Q8IMX8_DROME (1-103): 1.86e-39: 128: 100.00		Q9W087_DROME (24-108): 2.98e-22: 85: 23.53
+	Dm
		1303486 Q8IMX8_DROME (1-103): 1.86e-39: 128: 100.00		Q9W2K2_DROME (24-107): 1.33e-21: 84.6: 26.19
+	Hs
		344526 LSM3_HUMAN (1-103): 4.33e-38: 125: 76.70		LSM8_HUMAN (24-107): 4.11e-23: 87.3: 28.57
+	Mm
		974304 LSM3_MOUSE (1-103): 4.33e-38: 125: 76.70		LSM8_MOUSE (24-107): 4.11e-23: 87.3: 28.57
+	Mm
		974306 LSM3_MOUSE (1-103): 4.33e-38: 125: 76.70		LSM1_MOUSE (23-109): 3.06e-22: 86.1: 26.44
+	Hs
		178011 LSM3_HUMAN (1-103): 4.33e-38: 125: 76.70		LSM1_HUMAN (23-109): 3.23e-22: 85.7: 26.44
+	Hs
		574210 RSMN_HUMAN (24-103): 3.92e-27: 101: 21.43		RSMB_HUMAN (24-95): 2.41e-23: 91.5: 27.40
+	Hs
		574132 RSMB_HUMAN (24-103): 1.28e-26: 99.7: 21.43		RSMB_HUMAN (24-95): 2.41e-23: 91.5: 27.40
+	Hs
		974112 RSMN_HUMAN (24-103): 3.92e-27: 101: 21.43		RUXG_HUMAN (18-100): 2.35e-24: 89.6: 32.53
+	Hs
		574202 RSMB_HUMAN (24-103): 1.28e-26: 99.7: 21.43		RUXG_HUMAN (18-100): 2.35e-24: 89.6: 32.53
+	Hs
		344531 RSMN_HUMAN (24-103): 3.92e-27: 101: 21.43		LSM8_HUMAN (24-107): 4.11e-23: 87.3: 28.57
+	Hs
		344509 RSMB_HUMAN (24-103): 1.28e-26: 99.7: 21.43		LSM8_HUMAN (24-107): 4.11e-23: 87.3: 28.57
+	Hs
		177994 RSMB_HUMAN (24-103): 1.28e-26: 99.7: 21.43		LSM1_HUMAN (23-109): 3.23e-22: 85.7: 26.44
+	Hs
		71570 RSMN_HUMAN (24-103): 3.92e-27: 101: 21.43		RUXGL_HUMAN (18-100): 3.58e-22: 84.2: 31.33
+	Hs
		71558 RSMB_HUMAN (24-103): 1.28e-26: 99.7: 21.43		RUXGL_HUMAN (18-100): 3.58e-22: 84.2: 31.33
+	Sp
		1491878 LSM3_SCHPO (10-99): 5.4e-30: 104: 60.00		LSM3_SCHPO (19-96): 1.98e-15: 67.4: 28.92
+	Sp
		267758 LSM3_SCHPO (10-99): 5.4e-30: 104: 60.00		LSM8_SCHPO (22-95): 6.92e-13: 61.2: 27.03