HitPredict

Interactor 1: LSM3 (P62311)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSM3

Interactor 2: LSM8 (Q6ZWM4)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0046540 - U4/U6 x U5 tri-snRNP complex GO:0071005 - U2-type precatalytic spliceosome GO:0120115 - Lsm2-8 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 102 Mm			1 96
+	Hs
		344526 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		LSM8_HUMAN (1-96): 2.63e-34: 114: 100.00
+	Dm
		1303485 Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70		Q9W087_DROME (3-96): 7.13e-33: 111: 69.15
+	Hs
		974292 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		LSM7_HUMAN (4-85): 9.51e-28: 98.4: 30.23
+	Hs
		178011 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		LSM1_HUMAN (2-91): 1.8e-25: 93.8: 33.33
+	Mm
		974306 LSM3_MOUSE (1-102): 8.92e-41: 131: 100.00		LSM1_MOUSE (2-91): 1.92e-25: 93.4: 33.33
+	Hs
		574203 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		RSMB_HUMAN (2-82): 1.56e-23: 91.5: 27.59
+	Hs
		974106 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		RUXG_HUMAN (3-75): 1.7e-23: 86.8: 24.66
+	Dm
		1303486 Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70		Q9W2K2_DROME (2-91): 1.56e-25: 93.8: 32.22
+	Dm
		1303480 Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70		Q9VJI7_DROME (4-85): 2.77e-24: 89.9: 27.59
+	Hs
		344531 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		LSM8_HUMAN (1-96): 2.63e-34: 114: 100.00
+	Dm
		1477039 SMD2_DROME (13-95): 3.13e-27: 97.8: 30.23		Q9W087_DROME (3-96): 7.13e-33: 111: 69.15
+	Sp
		267758 LSM3_SCHPO (9-98): 2.03e-30: 105: 57.78		LSM8_SCHPO (4-96): 2.86e-29: 102: 46.24
+	Hs
		177994 RSMB_HUMAN (23-102): 1.48e-24: 94.3: 23.81		LSM1_HUMAN (2-91): 1.8e-25: 93.8: 33.33
+	Hs
		574210 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		RSMB_HUMAN (2-82): 1.56e-23: 91.5: 27.59
+	Ce
		198255 O18694_CAEEL (17-91): 2.98e-26: 94.7: 34.67		Q23543_CAEEL (4-89): 4.61e-25: 91.8: 26.67
+	Dm
		1052576 SMD2_DROME (13-95): 3.13e-27: 97.8: 30.23		RSMB_DROME (3-70): 9.01e-23: 88.4: 29.73
+	Hs
		974112 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		RUXG_HUMAN (3-75): 1.7e-23: 86.8: 24.66
+	Dm
		1477033 SMD2_DROME (13-95): 3.13e-27: 97.8: 30.23		RUXG_DROME (3-75): 1.15e-22: 84.9: 21.92
+	Hs
		71570 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		RUXGL_HUMAN (3-75): 1.82e-21: 81.8: 24.66
+	Hs
		71558 RSMB_HUMAN (23-102): 1.48e-24: 94.3: 23.81		RUXGL_HUMAN (3-75): 1.82e-21: 81.8: 24.66