HitPredict

Interactor 1: SIAH1 (Q8IUQ4)
E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a)
Gene: SIAH1

Interactor 2: SNCAP (Q9Y6H5)
Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein)
Gene: SNCAIP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.660

The method score is based on:

Property Details
Experiments 15064394, 14506261
Identification Methods affinity chromatography technology, enzymatic study, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, ubiquitination reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 282
Hs

1 919
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025