HitPredict

Interactor 1: ARMC8 (Q8IUR7)
Armadillo repeat-containing protein 8
Gene: ARMC8

Interactor 2: PKP4 (Q99569)
Plakophilin-4 (p0071)
Gene: PKP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	30482882, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Arm~Arm
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 1192
+	Mm
		1229329 SPAG6_MOUSE (61-298): 8.21e-13: 73.2: 19.25		PKP4_MOUSE (1-1192): 0: 1130: 96.48
+	Hs
		1307910 ARMC8_HUMAN (1-673): 3.85e-127: 393: 100.00		PKP2_HUMAN (156-1014): 3.13e-160: 501: 24.78
+	Hs
		1307961 ARMC8_HUMAN (1-673): 3.85e-127: 393: 100.00		PKP3_HUMAN (218-1014): 3.22e-152: 478: 26.92
+	Hs
		764876 ARMC8_HUMAN (1-673): 3.85e-127: 393: 100.00		CTNB1_HUMAN (311-1123): 7.92e-149: 468: 16.00
+	Hs
		1117959 ARMC8_HUMAN (1-673): 3.85e-127: 393: 100.00		PKP1_HUMAN (413-1009): 4.24e-124: 401: 28.59
+	Hs
		253630 IMA7_HUMAN (152-547): 2.33e-34: 139: 13.22		TRIPC_HUMAN (110-1126): 9.39e-126: 429: 11.99
+	Hs
		179045 IMA6_HUMAN (389-673): 1.01e-32: 134: 17.30		TRIPC_HUMAN (110-1126): 9.39e-126: 429: 11.99
+	Hs
		911245 IMA5_HUMAN (152-547): 6.79e-28: 120: 13.22		TRIPC_HUMAN (110-1126): 9.39e-126: 429: 11.99