HitPredict

Interactor 1: PCGF6 (Q99NA9)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Interactor 2: Q9DCC5 (Q9DCC5)
Cbx3 protein (Chromobox 3)
Gene: Cbx3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 353 Mm			1 183
+	Hs
		1027241 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Mm
		1143044 PCGF6_MOUSE (1-353): 3.18e-86: 266: 100.00		CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89
+	Mm
		949960 PCGF6_MOUSE (1-353): 3.18e-86: 266: 100.00		CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33
+	Hs
		800514 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		717776 BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		949876 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		717529 BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Mm
		1257536 PCGF6_MOUSE (1-353): 3.18e-86: 266: 100.00		CBX7_MOUSE (21-101): 5.72e-26: 99.1: 35.29
+	Hs
		327861 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX7_HUMAN (21-181): 5.6e-29: 109: 22.78
+	Hs
		123317 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		316144 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Hs
		1316705 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX8_HUMAN (21-116): 2.34e-26: 104: 32.00
+	Hs
		1059190 PCGF6_HUMAN (45-353): 1.29e-79: 249: 93.55		CBX2_HUMAN (20-117): 5.97e-25: 102: 27.00
+	Hs
		327830 BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71		CBX7_HUMAN (21-181): 5.6e-29: 109: 22.78
+	Hs
		123193 BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		315976 BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71		CBX6_HUMAN (21-124): 3.3e-27: 107: 27.78
+	Dr
		1193374 BMI1A_DANRE (120-352): 1.96e-65: 211: 35.83		Q804D1_DANRE (21-106): 6.82e-25: 101: 31.11
+	Hs
		718213 BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71		CBX8_HUMAN (21-116): 2.34e-26: 104: 32.00
+	Dr
		1186372 BMI1B_DANRE (120-352): 1.32e-64: 209: 34.86		Q804D1_DANRE (21-106): 6.82e-25: 101: 31.11
+	Hs
		717831 BMI1_HUMAN (120-352): 9.29e-64: 207: 34.71		CBX2_HUMAN (20-117): 5.97e-25: 102: 27.00