HitPredict

Interactor 1: FYCO1 (Q9BQS8)
FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
Gene: FYCO1

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.738

Property	Details
Experiments	31006538, 35271311, 20562859, 23043107, 24089205, 20100911
Identification Methods	affinity chromatography technology, unspecified method, tandem affinity purification, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1478 Hs			1 125
+	Hs
		1309824 FYCO1_HUMAN (1-1478): 4.9e-142: 475: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891297 FYCO1_HUMAN (1-1478): 4.9e-142: 475: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306297 FYCO1_HUMAN (1-1478): 4.9e-142: 475: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1309818 FYCO1_HUMAN (1-1478): 4.9e-142: 475: 100.00		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1309822 FYCO1_HUMAN (1-1478): 4.9e-142: 475: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		725011 MYH9_HUMAN (1-843): 7.74e-35: 148: 11.32		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		551829 DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		551835 DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		551651 DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305947 DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		551832 DESP_HUMAN (232-1121): 6.82e-14: 79.7: 22.05		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1068655 PLEC_HUMAN (385-1169): 2.58e-09: 64.7: 22.38		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1169304 RUFY4_HUMAN (1032-1228): 2.09e-09: 64.2: 21.32		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1068658 PLEC_HUMAN (385-1169): 2.58e-09: 64.7: 22.38		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46