HitPredict

Interactor 1: SSBP4 (Q9BWG4)
Single-stranded DNA-binding protein 4
Gene: SSBP4

Interactor 2: LHX3 (Q9UBR4)
LIM/homeobox protein Lhx3 (LIM homeobox protein 3)
Gene: LHX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 385 Hs			1 397
+	Hs
		238118 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LMX1B_HUMAN (1-339): 4.26e-64: 212: 28.54
+	Hs
		822672 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LHX1_HUMAN (31-396): 6.18e-62: 206: 32.21
+	Hs
		1314654 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LHX9_HUMAN (4-154): 9.27e-51: 176: 41.56
+	Hs
		899932 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		ISL1_HUMAN (21-309): 5.65e-50: 173: 27.60
+	Hs
		1148490 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LHX8_HUMAN (30-290): 3.86e-49: 171: 29.12
+	Hs
		1251453 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LMO3_HUMAN (31-159): 1.12e-51: 171: 41.05
+	Mm
		291998 Q3U4B1_MOUSE (1-385): 1.89e-54: 185: 83.68		LMX1B_MOUSE (1-339): 4.48e-65: 214: 28.50
+	Hs
		638570 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		RBTN1_HUMAN (31-149): 1.03e-50: 169: 42.74
+	Hs
		238119 SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03		LMX1B_HUMAN (1-339): 4.26e-64: 212: 28.54
+	Hs
		1283495 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		ISL2_HUMAN (21-321): 3.61e-46: 164: 27.75
+	Hs
		1314660 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LHX6_HUMAN (14-253): 5.91e-46: 163: 31.18
+	Hs
		822674 SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03		LHX1_HUMAN (31-396): 6.18e-62: 206: 32.21
+	Mm
		1112385 Q3U4B1_MOUSE (1-385): 1.89e-54: 185: 83.68		LHX9_MOUSE (4-154): 8.24e-50: 174: 41.56
+	Hs
		638571 SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03		RBTN1_HUMAN (31-149): 1.03e-50: 169: 42.74
+	Mm
		1112383 Q3U4B1_MOUSE (1-385): 1.89e-54: 185: 83.68		ISL2_MOUSE (21-321): 9.38e-46: 162: 27.75
+	Hs
		903772 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LMO4_HUMAN (31-148): 2.3e-28: 110: 43.09
+	Hs
		839818 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LHX2_HUMAN (136-281): 4.68e-15: 77.9: 23.90
+	Hs
		1281178 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		LHX4_HUMAN (8-83): 1.09e-13: 73.9: 25.00
+	Hs
		839819 SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03		LHX2_HUMAN (136-281): 4.68e-15: 77.9: 23.90
+	Hs
		110821 SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03		H7C0H1_HUMAN (136-281): 8.57e-15: 77.2: 23.90