HitPredict

Interactor 1: TRI22 (Q8IYM9)
E3 ubiquitin-protein ligase TRIM22 (EC 2.3.2.27) (50 kDa-stimulated trans-acting factor) (RING finger protein 94) (RING-type E3 ubiquitin transferase TRIM22) (Staf-50) (Tripartite motif-containing protein 22)
Gene: TRIM22

Interactor 2: TRI22 (Q8IYM9)
E3 ubiquitin-protein ligase TRIM22 (EC 2.3.2.27) (50 kDa-stimulated trans-acting factor) (RING finger protein 94) (RING-type E3 ubiquitin transferase TRIM22) (Staf-50) (Tripartite motif-containing protein 22)
Gene: TRIM22

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 17156811
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 22 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 498
Hs

1 498
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Service provided by Combinatics, Japan

Last updated: 11Aug2025