HitPredict

Interactor 1: Q3U7K7 (Q3U7K7)
E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (Tripartite motif-containing protein 21)
Gene: Trim21

Interactor 2: RO52 (Q62191)
E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21)
Gene: Trim21

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 23222971
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~PRY, PRY~SPRY, SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-C3HC4, zf-C3HC4~zf-C3HC4
Common GO terms GO:0006513 - protein monoubiquitination
GO:0008270 - zinc ion binding
GO:0010494 - cytoplasmic stress granule
GO:0010508 - positive regulation of autophagy
GO:0031648 - protein destabilization
and 8 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 462
Mm

1 470
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Last updated: 11Aug2025