Interactor 1: KRIT1 (O00522)
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)
Gene: KRIT1
Interactor 2: ITBP1 (O14713)
Integrin beta-1-binding protein 1 (Integrin cytoplasmic domain-associated protein 1) (ICAP-1)
Gene: ITGB1BP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.90 | 0.923 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25814554, 11741838, 11854171, 25910212, 28514442, 33961781, unassigned1126 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, two hybrid array, two hybrid bait and prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ICAP-1_inte_bdg~NUDIX_5 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0033622 - integrin activation |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
