Interactor 1: MLKL (Q9D2Y4)
Mixed lineage kinase domain-like protein
Gene: MLKL

Interactor 2: RIPK3 (Q9QZL0)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3)
Gene: RIPK3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 26559832, 22265413
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0044877 - protein-containing complex binding
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 472
Mm

1 486
+ At
+ At
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024