HitPredict

Interactor 1: LRC18 (Q8N456)
Leucine-rich repeat-containing protein 18
Gene: LRRC18

Interactor 2: KCD17 (Q8N5Z5)
BTB/POZ domain-containing protein KCTD17
Gene: KCTD17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	16189514
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 314
+	Mm
		595222 SCRIB_MOUSE (2-255): 2.6e-58: 201: 21.35		KCNA3_MOUSE (7-281): 1.77e-75: 242: 14.59
+	Hs
		1122302 SCRIB_HUMAN (1-204): 8.51e-42: 154: 23.81		KCNB2_HUMAN (3-260): 2.14e-75: 249: 17.91
+	Hs
		643032 LRRC7_HUMAN (1-185): 2.6e-43: 158: 26.70		KCNA3_HUMAN (7-281): 7.86e-75: 241: 15.30
+	Hs
		642862 SCRIB_HUMAN (1-204): 8.51e-42: 154: 23.81		KCNA3_HUMAN (7-281): 7.86e-75: 241: 15.30
+	Hs
		643035 ERBIN_HUMAN (2-185): 2.82e-41: 152: 28.95		KCNA3_HUMAN (7-281): 7.86e-75: 241: 15.30
+	Hs
		648822 SCRIB_HUMAN (1-204): 8.51e-42: 154: 23.81		KCNA5_HUMAN (24-264): 1.31e-67: 223: 13.51
+	Hs
		648835 ERBIN_HUMAN (2-185): 2.82e-41: 152: 28.95		KCNA5_HUMAN (24-264): 1.31e-67: 223: 13.51
+	Hs
		648775 SCRIB_HUMAN (1-204): 8.51e-42: 154: 23.81		KCNA4_HUMAN (12-264): 2.27e-65: 218: 14.77
+	Hs
		648792 ERBIN_HUMAN (2-185): 2.82e-41: 152: 28.95		KCNA4_HUMAN (12-264): 2.27e-65: 218: 14.77
+	Mm
		1281992 SCRIB_MOUSE (2-255): 2.6e-58: 201: 21.35		BACD1_MOUSE (1-178): 2.1e-45: 158: 26.53
+	Hs
		595061 LRC8E_HUMAN (27-252): 2.09e-18: 86.4: 21.80		KCNA2_HUMAN (3-281): 6.31e-75: 239: 13.01
+	Hs
		643075 LRC40_HUMAN (2-235): 2.46e-16: 80.1: 14.74		KCNA3_HUMAN (7-281): 7.86e-75: 241: 15.30
+	Ce
		263989 LAP1_CAEEL (2-159): 7.76e-29: 116: 22.56		Q18776_CAEEL (9-209): 9.7e-63: 201: 50.25
+	Mm
		1281879 ERBIN_MOUSE (2-185): 5.47e-41: 152: 28.42		BACD1_MOUSE (1-178): 2.1e-45: 158: 26.53
+	Hs
		1122291 SCRIB_HUMAN (1-204): 8.51e-42: 154: 23.81		SHKB1_HUMAN (14-122): 4.01e-38: 145: 44.95
+	Mm
		1296388 FLII_MOUSE (2-187): 2.68e-34: 132: 21.10		BACD1_MOUSE (1-178): 2.1e-45: 158: 26.53
+	Mm
		1190572 LRCH2_MOUSE (77-248): 2.11e-23: 101: 19.19		BACD1_MOUSE (1-178): 2.1e-45: 158: 26.53
+	Mm
		1281868 LRRC7_MOUSE (169-261): 1.23e-09: 60.4: 10.53		BACD1_MOUSE (1-178): 2.1e-45: 158: 26.53
+	Mm
		1296036 LRCH3_MOUSE (125-249): 8.16e-09: 57.9: 14.69		BACD1_MOUSE (1-178): 2.1e-45: 158: 26.53