HitPredict

Interactor 1: KCNA4 (P22459)
Potassium voltage-gated channel subfamily A member 4 (HPCN2) (Voltage-gated K(+) channel HuKII) (Voltage-gated potassium channel HBK4) (Voltage-gated potassium channel HK1) (Voltage-gated potassium channel subunit Kv1.4)
Gene: KCNA4

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 1655
+	Hs
		642862 KCNA3_HUMAN (84-653): 1.06e-157: 467: 60.59		SCRIB_HUMAN (1-1655): 0: 940: 100.00
+	Hs
		648766 KCNA4_HUMAN (1-653): 0: 603: 100.00		DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42
+	Rn
		583946 KCNA4_RAT (1-653): 0: 599: 96.34		DLG4_RAT (812-1187): 5.61e-49: 189: 22.42
+	Mm
		1222743 KCNA4_MOUSE (1-653): 0: 584: 97.10		DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42
+	Hs
		648789 KCNA4_HUMAN (1-653): 0: 603: 100.00		DLG3_HUMAN (724-947): 1.79e-19: 97.4: 31.23
+	Rn
		583947 KCNA4_RAT (1-653): 0: 599: 96.34		DLG3_RAT (724-947): 3.66e-19: 96.3: 31.23
+	Hs
		648776 KCNA4_HUMAN (1-653): 0: 603: 100.00		DLG2_HUMAN (591-851): 2.07e-16: 87.5: 16.79
+	Hs
		648769 KCNA4_HUMAN (1-653): 0: 603: 100.00		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		648792 KCNA4_HUMAN (1-653): 0: 603: 100.00		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		642796 KCNA3_HUMAN (84-653): 1.06e-157: 467: 60.59		DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42
+	Hs
		595035 KCNA2_HUMAN (140-653): 5.55e-154: 455: 65.95		DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42
+	Mm
		990946 KCNA2_MOUSE (140-653): 2.41e-154: 456: 65.95		DLG4_MOUSE (812-1187): 1.23e-48: 188: 22.42
+	Hs
		1006055 KCNA1_HUMAN (140-653): 1.23e-151: 449: 66.15		DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42
+	Hs
		648813 KCNA5_HUMAN (50-636): 3.53e-150: 449: 54.98		DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42
+	Hs
		299734 KCNA3_HUMAN (84-653): 1.06e-157: 467: 60.59		MPDZ_HUMAN (785-1091): 2.82e-25: 117: 21.98
+	Hs
		643075 KCNA3_HUMAN (84-653): 1.06e-157: 467: 60.59		LRC40_HUMAN (13-349): 4.24e-21: 101: 25.80
+	Rn
		618300 KCNA5_RAT (44-636): 9.39e-152: 453: 55.28		DLG1_RAT (955-1182): 3.1e-24: 112: 37.56
+	Hs
		642835 KCNA3_HUMAN (84-653): 1.06e-157: 467: 60.59		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		643035 KCNA3_HUMAN (84-653): 1.06e-157: 467: 60.59		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Hs
		643032 KCNA3_HUMAN (84-653): 1.06e-157: 467: 60.59		LRRC7_HUMAN (816-951): 5.37e-09: 63.6: 27.54