HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	11751856, 33545068, 15388348
Identification Methods	pull down, proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	C2~C2
Common GO terms	GO:0005150 - interleukin-1, type I receptor binding GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005769 - early endosome GO:0005829 - cytosol and 25 others more... GO:0006511 - ubiquitin-dependent protein catabolic process GO:0006914 - autophagy GO:0006954 - inflammatory response GO:0007165 - signal transduction GO:0016310 - phosphorylation GO:0016604 - nuclear body GO:0019897 - extrinsic component of plasma membrane GO:0019900 - kinase binding GO:0030855 - epithelial cell differentiation GO:0031624 - ubiquitin conjugating enzyme binding GO:0031625 - ubiquitin protein ligase binding GO:0032183 - SUMO binding GO:0032991 - protein-containing complex GO:0033235 - positive regulation of protein sumoylation GO:0035325 - Toll-like receptor binding GO:0035578 - azurophil granule lumen GO:0035580 - specific granule lumen GO:0036010 - protein localization to endosome GO:0043130 - ubiquitin binding GO:0045087 - innate immune response GO:0045321 - leukocyte activation GO:0048471 - perinuclear region of cytoplasm GO:0060090 - molecular adaptor activity GO:0070062 - extracellular exosome GO:0070498 - interleukin-1-mediated signaling pathway
Homologous interactions	1