HitPredict

Interactor 1: ZC3H8 (Q8N5P1)
Zinc finger CCCH domain-containing protein 8
Gene: ZC3H8

Interactor 2: ZCRB1 (Q8TBF4)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K)
Gene: ZCRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 291 Hs			1 217
+	Hs
		1313100 ZC3H3_HUMAN (105-274): 2.3e-23: 101: 19.81		ZCRB1_HUMAN (1-217): 2.04e-56: 180: 100.00
+	Hs
		1313146 ZC3H3_HUMAN (105-274): 2.3e-23: 101: 19.81		PABP3_HUMAN (3-181): 1.18e-44: 158: 18.65
+	Hs
		1387886 MKRN2_HUMAN (194-287): 2.2e-27: 111: 27.37		PABP5_HUMAN (5-179): 8.23e-39: 139: 15.87
+	Dm
		1472288 CPSF4_DROME (171-276): 1.84e-25: 104: 20.35		Q9VE52_DROME (10-132): 4.67e-32: 121: 21.14
+	Hs
		272983 ZC11A_HUMAN (195-268): 4.41e-18: 86: 28.40		PABP5_HUMAN (5-179): 8.23e-39: 139: 15.87
+	Hs
		1102088 MKRN2_HUMAN (194-287): 2.2e-27: 111: 27.37		PABP4_HUMAN (11-99): 3.6e-23: 98.9: 17.98
+	Hs
		550458 MKRN2_HUMAN (194-287): 2.2e-27: 111: 27.37		PABP1_HUMAN (11-99): 2.66e-22: 96.2: 19.10
+	Hs
		1387908 MKRN1_HUMAN (222-271): 5e-10: 61.8: 25.46		PABP5_HUMAN (5-179): 8.23e-39: 139: 15.87
+	Hs
		1102014 ZC3H3_HUMAN (105-274): 2.3e-23: 101: 19.81		PABP4_HUMAN (11-99): 3.6e-23: 98.9: 17.98
+	Hs
		1416115 MKRN2_HUMAN (194-287): 2.2e-27: 111: 27.37		RBM4_HUMAN (11-103): 1.52e-18: 84.2: 21.51
+	Hs
		340775 CPSF4_HUMAN (180-248): 3.01e-09: 58.7: 20.00		CSTFT_HUMAN (10-132): 8.39e-33: 126: 22.58
+	Hs
		340751 CPSF4_HUMAN (180-248): 3.01e-09: 58.7: 20.00		SRSF7_HUMAN (9-120): 7.58e-35: 125: 32.17
+	Hs
		272872 ZC11A_HUMAN (195-268): 4.41e-18: 86: 28.40		PABP1_HUMAN (11-99): 2.66e-22: 96.2: 19.10
+	Hs
		340729 CPSF4_HUMAN (180-248): 3.01e-09: 58.7: 20.00		CSTF2_HUMAN (10-132): 3.68e-31: 121: 23.39
+	Hs
		1102126 MKRN1_HUMAN (222-271): 5e-10: 61.8: 25.46		PABP4_HUMAN (11-99): 3.6e-23: 98.9: 17.98
+	Hs
		550506 MKRN1_HUMAN (222-271): 5e-10: 61.8: 25.46		PABP1_HUMAN (11-99): 2.66e-22: 96.2: 19.10
+	Hs
		1029048 MKRN1_HUMAN (222-271): 5e-10: 61.8: 25.46		TIAR_HUMAN (3-142): 1.82e-18: 84.3: 14.89