Interactor 1: KBTB8 (Q8NFY9)
Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP)
Gene: KBTBD8
Interactor 2: GAN (Q9H2C0)
Gigaxonin (Kelch-like protein 16)
Gene: GAN
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 1.00 | 0.855 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 33961781, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BACK~BTB, BTB~BTB, BACK~Kelch_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031463 - Cul3-RING ubiquitin ligase complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:1990756 - ubiquitin-like ligase-substrate adaptor activity |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
