Protein: KLH25
Kelch-like protein 25 (Ectoderm-neural cortex protein 2) (ENC-2)

Gene: KLH25, KLHL25
Organism: Homo sapiens
Interactions: 23
UniProt ID: Q9H0H3

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006446 - regulation of translational initiation
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114259

CUL3
Cullin-3

11

20

Small-scale

0.974

High

161307

ENC1
Ectoderm-neural cortex protein 1

3

19

High-throughput

0.855

High

1419348

BACH2
Transcription regulator protein BACH2

1

19

High-throughput

0.691

High

1382699

EMID1
EMI domain-containing protein 1

4

5

High-throughput

0.630

High

920888

ACLY
ATP-citrate synthase

2

0

Small-scale

0.607

High

766119

PCGF2
Polycomb group RING finger protein 2

3

1

High-throughput

0.604

High

1430055

M1IP1
Mid1-interacting protein 1

2

0

High-throughput

0.576

High

1112707

CUL1
Cullin-1

1

20

High-throughput

0.575

High

1430056

KLHL9
Kelch-like protein 9

1

20

High-throughput

0.575

High

1430057

KLH13
Kelch-like protein 13

1

20

High-throughput

0.575

High

1430059

FXL17
F-box/LRR-repeat protein 17

1

15

High-throughput

0.575

High

543437

PSG1
Pregnancy-specific beta-1-glycoprotein 1

2

4

High-throughput

0.574

High

1290366

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

3

High-throughput

0.558

High

1146474

KS6A2
Ribosomal protein S6 kinase alpha-2

1

5

High-throughput

0.536

High

1200011

KLH26
Kelch-like protein 26

1

20

High-throughput

0.514

High

461919

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

468787

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

1109568

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

1

Small-scale

0.479

High

1308585

NUDC3
NudC domain-containing protein 3

1

20

High-throughput

0.479

High

1430060

ARI1
E3 ubiquitin-protein ligase ARIH1

1

11

High-throughput

0.479

High

1147274

ELOB
Elongin-B

1

0

High-throughput

0.458

High

1430058

DNJB4
DnaJ homolog subfamily B member 4

1

4

High-throughput

0.445

High

76575

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

5

High-throughput

0.437

High


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Last updated: 11Aug2025