HitPredict

Interactor 1: DDX55 (Q8NHQ9)
ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55)
Gene: DDX55

Interactor 2: WDR89 (Q96FK6)
WD repeat-containing protein 89
Gene: WDR89

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Helicase_C~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 600 Hs			1 387
+	Hs
		965274 DDX18_HUMAN (7-511): 8.82e-143: 431: 33.99		WDR5_HUMAN (150-385): 7.16e-50: 172: 11.11
+	Sc
		673547 SPB4_YEAST (9-566): 3.01e-159: 470: 37.44		NLE1_YEAST (6-146): 3.24e-31: 125: 16.08
+	Hs
		1387591 DDX18_HUMAN (7-511): 8.82e-143: 431: 33.99		SNR40_HUMAN (6-197): 8.44e-38: 141: 16.24
+	Hs
		965133 DDX17_HUMAN (8-485): 2.86e-130: 400: 25.31		WDR5_HUMAN (150-385): 7.16e-50: 172: 11.11
+	Sc
		678362 SPB4_YEAST (9-566): 3.01e-159: 470: 37.44		PWP2_YEAST (34-349): 1.05e-18: 90.3: 11.32
+	Hs
		608525 DDX5_HUMAN (8-401): 3e-126: 386: 27.34		WDR5_HUMAN (150-385): 7.16e-50: 172: 11.11
+	Hs
		1369343 DDX17_HUMAN (8-485): 2.86e-130: 400: 25.31		SNR40_HUMAN (6-197): 8.44e-38: 141: 16.24
+	Sc
		632627 DBP4_YEAST (4-587): 6.84e-148: 447: 30.80		PWP2_YEAST (34-349): 1.05e-18: 90.3: 11.32
+	Hs
		141400 DDX3X_HUMAN (7-403): 3.85e-117: 364: 30.53		WDR5_HUMAN (150-385): 7.16e-50: 172: 11.11
+	Hs
		608695 DDX5_HUMAN (8-401): 3e-126: 386: 27.34		SNR40_HUMAN (6-197): 8.44e-38: 141: 16.24
+	Hs
		1369337 DDX17_HUMAN (8-485): 2.86e-130: 400: 25.31		FBXW7_HUMAN (198-387): 1.12e-30: 125: 11.34
+	Sc
		673587 HAS1_YEAST (8-483): 6.84e-131: 394: 34.79		NLE1_YEAST (6-146): 3.24e-31: 125: 16.08
+	Hs
		1369406 DDX17_HUMAN (8-485): 2.86e-130: 400: 25.31		NLE1_HUMAN (253-386): 3e-26: 111: 14.38
+	Hs
		141604 DDX3X_HUMAN (7-403): 3.85e-117: 364: 30.53		FBXW7_HUMAN (198-387): 1.12e-30: 125: 11.34
+	Sc
		678448 HAS1_YEAST (8-483): 6.84e-131: 394: 34.79		PWP2_YEAST (34-349): 1.05e-18: 90.3: 11.32
+	Sc
		444437 DED1_YEAST (10-405): 9.66e-117: 361: 29.93		PWP2_YEAST (34-349): 1.05e-18: 90.3: 11.32
+	Hs
		965230 DDX47_HUMAN (23-372): 7.07e-57: 199: 37.04		WDR5_HUMAN (150-385): 7.16e-50: 172: 11.11
+	Hs
		1387564 DDX31_HUMAN (16-462): 1.04e-59: 215: 31.05		SNR40_HUMAN (6-197): 8.44e-38: 141: 16.24
+	Hs
		302963 DDX31_HUMAN (16-462): 1.04e-59: 215: 31.05		CIAO1_HUMAN (101-350): 6.52e-38: 141: 14.00
+	Hs
		1436289 DDX31_HUMAN (16-462): 1.04e-59: 215: 31.05		NLE1_HUMAN (253-386): 3e-26: 111: 14.38