HitPredict

Interactor 1: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Interactor 2: SPN90 (Q9NZQ3)
NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein)
Gene: NCKIPSD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0007010 - cytoskeleton organization GO:0017124 - SH3 domain binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 722
+	Hs
		1052337 SRC8_HUMAN (271-507): 2.78e-32: 131: 17.84		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		1066054 ARHG6_HUMAN (408-508): 2.64e-22: 102: 29.81		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		1049739 ARHG7_HUMAN (451-508): 2.16e-18: 90.8: 41.38		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		924910 GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		1349276 ITSN2_HUMAN (289-512): 5.53e-14: 77.2: 15.63		SPN90_HUMAN (1-722): 0: 1137: 100.00
+	Hs
		1078920 ITSN1_HUMAN (380-510): 4.82e-12: 71: 15.22		SPN90_HUMAN (1-722): 0: 1137: 100.00