HitPredict

Interactor 1: ES8L1 (Q8TE68)
Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8-like protein 1) (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-related protein 1)
Gene: EPS8L1

Interactor 2: NUD12 (Q9BQG2)
NAD-capped RNA hydrolase NUDT12 (DeNADding enzyme NUDT12) (EC 3.6.1.-) (NADH pyrophosphatase NUDT12) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)
Gene: NUDT12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 723 Hs			1 462
+	Hs
		177208 EPS8_HUMAN (3-716): 0: 754: 34.96		ANR28_HUMAN (162-439): 2.8e-17: 86.8: 10.84
+	Hs
		463836 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		ANR50_HUMAN (2-174): 2.15e-30: 127: 19.65
+	Hs
		440239 LCK_HUMAN (417-701): 3.52e-67: 232: 15.36		KDIS_HUMAN (173-439): 5.31e-17: 86.4: 8.33
+	Hs
		440051 LCK_HUMAN (417-701): 3.52e-67: 232: 15.36		ANK3_HUMAN (280-459): 2.04e-15: 81.4: 12.90
+	Hs
		463458 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		ANK2_HUMAN (162-454): 6.14e-24: 107: 9.38
+	Hs
		440199 LCK_HUMAN (417-701): 3.52e-67: 232: 15.36		TANC1_HUMAN (2-235): 1.34e-12: 72.5: 14.09
+	Hs
		440813 FYN_HUMAN (430-704): 9.82e-56: 201: 13.07		MYO16_HUMAN (10-220): 2.67e-18: 90.2: 13.68
+	Hs
		463835 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		KDIS_HUMAN (173-439): 5.31e-17: 86.4: 8.33
+	Hs
		463487 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		ANK3_HUMAN (280-459): 2.04e-15: 81.4: 12.90
+	Hs
		463751 LYN_HUMAN (451-704): 2.55e-55: 199: 15.89		TANC1_HUMAN (2-235): 1.34e-12: 72.5: 14.09
+	Hs
		221990 NCK2_HUMAN (478-605): 1.6e-36: 143: 23.70		PSD10_HUMAN (20-233): 8.95e-23: 98.3: 16.74
+	Hs
		593966 NCK1_HUMAN (478-605): 5.22e-32: 130: 22.96		ANK2_HUMAN (162-454): 6.14e-24: 107: 9.38
+	Hs
		222130 NCK2_HUMAN (478-605): 1.6e-36: 143: 23.70		ANS1B_HUMAN (83-388): 4.9e-18: 89.5: 10.71
+	Hs
		222096 NCK2_HUMAN (478-605): 1.6e-36: 143: 23.70		ANR55_HUMAN (3-193): 3.31e-13: 73.7: 20.49
+	Hs
		222076 NCK2_HUMAN (478-605): 1.6e-36: 143: 23.70		ILK_HUMAN (9-100): 3.04e-11: 67.1: 28.26
+	Hs
		594080 NCK1_HUMAN (478-605): 5.22e-32: 130: 22.96		EHMT2_HUMAN (6-100): 1.29e-09: 62.9: 23.16