HitPredict

Interactor 1: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0030054 - cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1356 Hs			1 779
+	Hs
		1197033 PARD3_HUMAN (1-1356): 0: 706: 100.00		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		1314085 PARD3_HUMAN (1-1356): 0: 706: 100.00		AMOL1_HUMAN (1-766): 2.7e-42: 168: 40.22
+	Hs
		1217544 PARD3_HUMAN (1-1356): 0: 706: 100.00		MRCKA_HUMAN (242-732): 6.81e-18: 91.3: 12.33
+	Hs
		299764 MPDZ_HUMAN (426-543): 5.29e-21: 102: 34.75		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		299806 MPDZ_HUMAN (426-543): 5.29e-21: 102: 34.75		AMOL2_HUMAN (1-779): 8.18e-72: 252: 100.00
+	Hs
		1090138 PTN13_HUMAN (39-368): 1.89e-16: 87.8: 12.50		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Hs
		1197065 MAGI1_HUMAN (413-780): 3.17e-16: 87: 15.48		AMOT_HUMAN (1-740): 2.71e-70: 252: 32.32
+	Mm
		1224966 INADL_MOUSE (451-714): 2.2e-26: 120: 20.71		AMOL2_MOUSE (1-779): 1.29e-58: 215: 86.17
+	Hs
		1288683 MAGI2_HUMAN (68-1178): 1.7e-38: 159: 13.69		AMOL1_HUMAN (1-766): 2.7e-42: 168: 40.22
+	Mm
		1317343 MPDZ_MOUSE (452-543): 4.98e-21: 102: 42.39		AMOL2_MOUSE (1-779): 1.29e-58: 215: 86.17
+	Mm
		1224968 INADL_MOUSE (451-714): 2.2e-26: 120: 20.71		AMOL1_MOUSE (1-761): 1.08e-38: 157: 38.96
+	Mm
		1224967 INADL_MOUSE (451-714): 2.2e-26: 120: 20.71		AMOT_MOUSE (1-661): 2.49e-38: 155: 38.15
+	Hs
		299770 MPDZ_HUMAN (426-543): 5.29e-21: 102: 34.75		AMOL1_HUMAN (1-766): 2.7e-42: 168: 40.22
+	Mm
		1353863 MPDZ_MOUSE (452-543): 4.98e-21: 102: 42.39		AMOL1_MOUSE (1-761): 1.08e-38: 157: 38.96
+	Mm
		1353860 MPDZ_MOUSE (452-543): 4.98e-21: 102: 42.39		AMOT_MOUSE (1-661): 2.49e-38: 155: 38.15
+	Hs
		1314099 MAGI1_HUMAN (413-780): 3.17e-16: 87: 15.48		AMOL1_HUMAN (1-766): 2.7e-42: 168: 40.22
+	Mm
		1225771 PTN13_MOUSE (265-1002): 1.39e-17: 91.5: 16.56		AMOT_MOUSE (1-661): 2.49e-38: 155: 38.15
+	Mm
		1000204 DLG4_MOUSE (540-699): 7.92e-23: 107: 27.98		ROCK2_MOUSE (307-661): 3.27e-12: 72.4: 17.02
+	Hs
		1090198 PTN13_HUMAN (39-368): 1.89e-16: 87.8: 12.50		CING_HUMAN (175-776): 1.72e-17: 89.7: 9.97
+	Hs
		1401127 MAGI1_HUMAN (413-780): 3.17e-16: 87: 15.48		CING_HUMAN (175-776): 1.72e-17: 89.7: 9.97