Protein: MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2)

Gene: MAGI2
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q86UL8

Gene Ontology (top 5):
GO:0001750 - photoreceptor outer segment
GO:0001917 - photoreceptor inner segment
GO:0002092 - positive regulation of receptor internalization
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1204209

PDZ11
PDZ domain-containing protein 11

2

20

High-throughput

0.783

High

249164

DSCAM
Cell adhesion molecule DSCAM

1

20

High-throughput

0.698

High

472226

ADRB1
Beta-1 adrenergic receptor

3

20

Small-scale

0.678

High

1288695

RPGF2
Rap guanine nucleotide exchange factor 2

1

10

Small-scale

0.665

High

1288686

DSCL1
Cell adhesion molecule DSCAML1

1

20

Small-scale

0.656

High

292493

RHBL1
Rhomboid-related protein 1

2

4

High-throughput

0.628

High

951733

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

11

Small-scale

0.624

High

350664

DLGP3
Disks large-associated protein 3

2

20

High-throughput

0.606

High

574349

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

4

High-throughput

0.606

High

1288684

MORN4
MORN repeat-containing protein 4

2

4

High-throughput

0.606

High

1288693

DLGP2
Disks large-associated protein 2

2

20

High-throughput

0.606

High

932093

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.590

High

1288689

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

19

High-throughput

0.575

High

1288692

PKHF2
Pleckstrin homology domain-containing family F member 2

2

5

High-throughput

0.553

High

1288690

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

2

Small-scale

0.536

High

106199

APRIO
Alternative prion protein

2

6

High-throughput

0.533

High

928298

ATN1
Atrophin-1

1

17

Small-scale

0.527

High

1288688

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

724119

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.515

High

1288687

ARRD3
Arrestin domain-containing protein 3

1

20

Small-scale

0.508

High

1288694

PLXB3
Plexin-B3

1

11

Small-scale

0.508

High

155247

AGRB1
Adhesion G protein-coupled receptor B1

1

19

Small-scale

0.501

High

376618

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

2

Small-scale

0.501

High

762205

CRFR1
Corticotropin-releasing factor receptor 1

1

20

Small-scale

0.501

High

154399

DLGP1
Disks large-associated protein 1

1

20

High-throughput

0.481

High

227173

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

20

Small-scale

0.481

High

690102

AVR2A
Activin receptor type-2A

1

10

Small-scale

0.481

High

345087

RIGI
Antiviral innate immune response receptor RIG-I

1

11

High-throughput

0.479

High

613090

EGR1
Early growth response protein 1

1

9

High-throughput

0.479

High

667357

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

High-throughput

0.479

High

723010

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.479

High

764869

CTNB1
Catenin beta-1

1

20

Small-scale

0.479

High

1145747

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

Small-scale

0.479

High

1288683

AMOL1
Angiomotin-like protein 1

1

20

High-throughput

0.479

High

1288685

CIP2A
Protein CIP2A

1

11

High-throughput

0.479

High

1235210

Q6IS01
DLGAP1 protein

1

20

High-throughput

0.470

High

943980

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

11

High-throughput

0.457

High

404830

PRIO
Major prion protein

1

4

High-throughput

0.445

High

1288691

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.439

High

1148355

KS6A1
Ribosomal protein S6 kinase alpha-1

1

15

Small-scale

0.408

High


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Last updated: 11Aug2025