HitPredict

Interactor 1: CSN2 (Q8W207)
COP9 signalosome complex subunit 2 (Signalosome subunit 2) (Protein FUSCA 12)
Gene: CSN2

Interactor 2: CSN3 (Q8W575)
COP9 signalosome complex subunit 3 (Signalosome subunit 3) (Protein FUSCA 11)
Gene: CSN3

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	12615944, 15703063
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	COP9_hel_rpt~PCI, PCI~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 439 At			1 429
+	Mm
		312542 CSN2_MOUSE (6-437): 5.12e-117: 350: 61.34		CSN3_MOUSE (6-428): 1.1e-116: 349: 37.76
+	Hs
		958737 CSN2_HUMAN (6-437): 5.12e-117: 350: 61.34		CSN3_HUMAN (6-428): 3.11e-116: 347: 37.76
+	Dm
		1344394 CSN2_DROME (10-438): 2.25e-113: 341: 59.30		CSN3_DROME (6-428): 4.17e-102: 312: 31.39
+	Mm
		107986 G3UXW9_MOUSE (11-438): 1.81e-82: 264: 13.96		CSN3_MOUSE (6-428): 1.1e-116: 349: 37.76
+	Hs
		127919 CSN2_HUMAN (6-437): 5.12e-117: 350: 61.34		PSD11_HUMAN (55-393): 6.15e-81: 257: 13.19
+	Dm
		1267330 CSN2_DROME (10-438): 2.25e-113: 341: 59.30		PSD11_DROME (55-394): 6.39e-79: 252: 13.16
+	Hs
		958615 CSN2_HUMAN (6-437): 5.12e-117: 350: 61.34		CSN2_HUMAN (33-384): 4.62e-73: 237: 11.17
+	Hs
		127831 PSD11_HUMAN (29-438): 1.12e-90: 282: 18.62		PSMD3_HUMAN (47-424): 2.87e-96: 300: 20.51
+	Dm
		669698 PSD11_DROME (30-438): 6.78e-86: 270: 18.57		PSMD3_DROME (8-420): 9.73e-100: 308: 19.72
+	Dm
		1375260 CSN2_DROME (10-438): 2.25e-113: 341: 59.30		CSN2_DROME (36-384): 4.88e-68: 224: 12.09
+	Ce
		144591 CSN2_CAEEL (11-413): 2.47e-99: 307: 53.32		CSN3_CAEEL (2-428): 3.02e-77: 250: 17.28
+	An
		1202929 CSN2_EMENI (4-433): 3.96e-105: 322: 48.50		CSN2_EMENI (37-374): 8.13e-70: 230: 12.43
+	Zm
		6840 A0A1D6E9U1_MAIZE (33-438): 2.27e-87: 274: 19.18		A0A1D6E9U1_MAIZE (8-385): 5.32e-86: 270: 13.70
+	Ce
		144582 CSN2_CAEEL (11-413): 2.47e-99: 307: 53.32		CSN2_CAEEL (30-366): 1.13e-71: 235: 12.46
+	Hs
		127823 PSD11_HUMAN (29-438): 1.12e-90: 282: 18.62		PSD11_HUMAN (55-393): 6.15e-81: 257: 13.19
+	Mm
		107991 G3UXW9_MOUSE (11-438): 1.81e-82: 264: 13.96		CSN2_MOUSE (33-384): 4.62e-73: 237: 11.17
+	Dm
		1375262 CSN2_DROME (10-438): 2.25e-113: 341: 59.30		CSN4_DROME (72-396): 5.69e-44: 159: 11.44
+	Dm
		1267332 PSD11_DROME (30-438): 6.78e-86: 270: 18.57		CSN4_DROME (72-396): 5.69e-44: 159: 11.44