Interactor 1: PSMD3 (P25161)
Probable 26S proteasome non-ATPase regulatory subunit 3 (26S proteasome subunit S3) (Diphenol oxidase A2 component) (DOX-A2) (Regulatory particle non-ATPase 3)
Gene: Rpn3

Interactor 2: PSD11 (Q7KLV9)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory complex subunit p42B) (26S proteasome regulatory subunit Rpn6)
Gene: Rpn6

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, RPN6_C_helix~Rpn3_C
Common GO terms GO:0000502 - proteasome complex
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle
GO:0006511 - ubiquitin-dependent protein catabolic process
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 494
Dm

1 422
+ Hs
+ Dm
+ Hs
+ Hs
+ Sp
+ Ce
+ Sc
+ Mm
+ Hs
+ At
+ Dm
+ Mm
+ Hs
+ At
+ Dm
+ Mm
+ Dm
+ Hs

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Last updated: 11Aug2025