HitPredict

Interactor 1: CCH11 (Q8W5S1)
Cyclin-H1-1 (CycH1;1)
Gene: CYCH1-1

Interactor 2: CDKD1 (Q9C9U2)
Cyclin-dependent kinase D-1 (CDKD;1) (EC 2.7.11.22) (EC 2.7.11.23) (CDK-activating kinase 3-At) (CAK3-At)
Gene: CDKD-1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	15486101, 20407024
Identification Methods	two hybrid, protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cyclin_C_2~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 336 At			1 398
+	At
		1184306 CCB13_ARATH (8-322): 4e-85: 264: 14.11		CDKD3_ARATH (2-397): 1.45e-150: 433: 82.32
+	At
		1355727 CCH11_ARATH (1-336): 5.38e-84: 259: 100.00		CDKD3_ARATH (2-397): 1.45e-150: 433: 82.32
+	Hs
		573751 CCNB1_HUMAN (16-301): 4.85e-82: 257: 16.96		CDK2_HUMAN (8-303): 3.94e-142: 408: 47.32
+	Hs
		667764 CCNA1_HUMAN (32-295): 3.07e-80: 253: 17.39		CDK2_HUMAN (8-303): 3.94e-142: 408: 47.32
+	Hs
		573801 CCNB1_HUMAN (16-301): 4.85e-82: 257: 16.96		CDK3_HUMAN (8-293): 2.47e-139: 401: 47.92
+	At
		1184302 CCB13_ARATH (8-322): 4e-85: 264: 14.11		CDKD2_ARATH (1-341): 3.62e-135: 392: 68.97
+	At
		1355723 CCH11_ARATH (1-336): 5.38e-84: 259: 100.00		Q9CAG1_ARATH (1-344): 1.65e-131: 396: 38.03
+	At
		1355725 CCH11_ARATH (1-336): 5.38e-84: 259: 100.00		CDKC1_ARATH (4-385): 1.87e-133: 393: 32.93
+	At
		1355721 CCH11_ARATH (1-336): 5.38e-84: 259: 100.00		CDKD2_ARATH (1-341): 3.62e-135: 392: 68.97
+	At
		1355590 CCH11_ARATH (1-336): 5.38e-84: 259: 100.00		CDKC2_ARATH (4-378): 1.91e-132: 391: 34.26
+	Hs
		573777 CCNB1_HUMAN (16-301): 4.85e-82: 257: 16.96		CDK7_HUMAN (5-306): 5.68e-133: 386: 56.39
+	Hs
		443152 CCNB1_HUMAN (16-301): 4.85e-82: 257: 16.96		CDK1_HUMAN (8-294): 4.07e-133: 384: 48.28
+	Hs
		573802 CCNB1_HUMAN (16-301): 4.85e-82: 257: 16.96		CDK5_HUMAN (8-297): 4.85e-133: 384: 48.97
+	At
		663894 CCH11_ARATH (1-336): 5.38e-84: 259: 100.00		CDKA1_ARATH (8-294): 6.2e-132: 381: 47.77
+	Hs
		443299 CCNA1_HUMAN (32-295): 3.07e-80: 253: 17.39		CDK1_HUMAN (8-294): 4.07e-133: 384: 48.28
+	At
		663870 CCB12_ARATH (1-319): 1.95e-80: 253: 14.76		CDKA1_ARATH (8-294): 6.2e-132: 381: 47.77
+	Mm
		543009 CCNB1_MOUSE (16-299): 1.11e-79: 251: 16.38		CDK1_MOUSE (8-294): 2.16e-131: 380: 48.28
+	At
		1320093 CCH11_ARATH (1-336): 5.38e-84: 259: 100.00		CKB21_ARATH (9-299): 5.98e-126: 367: 42.53
+	At
		1184282 CCB12_ARATH (1-319): 1.95e-80: 253: 14.76		CKB21_ARATH (9-299): 5.98e-126: 367: 42.53
+	At
		1184283 CCB12_ARATH (1-319): 1.95e-80: 253: 14.76		CKB22_ARATH (11-299): 9.48e-126: 366: 42.48