Interactor 1: MD2L2 (Q9UI95)
Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7)
Gene: MAD2L2

Interactor 2: MD2L2 (Q9UI95)
Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7)
Gene: MAD2L2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.911

The method score is based on:

Property Details
Experiments 30111544, 29656893, 32811646, 11485998, 32332881
Identification Methods two hybrid, affinity chromatography technology, pull down, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HORMA~HORMA
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0001558 - regulation of cell growth
GO:0002208 - somatic diversification of immunoglobulins involved in immune response
GO:0005634 - nucleus
and 30 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 211
Hs

1 211
+ Hs
+ Dm
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024