HitPredict

Interactor 1: GOSR1 (Q9VE50)
Golgi SNAP receptor complex member 1 (Probable 28 kDa Golgi SNARE protein)
Gene: Gos28

Interactor 2: Q9VVX6 (Q9VVX6)
Blocked early in transport 1, isoform A (Blocked early in transport 1, isoform B) (RH40423p)
Gene: Bet1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	22036573, 19079254
Identification Methods	affinity chromatography technology, two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0005484 - SNAP receptor activity GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0015031 - protein transport GO:0031201 - SNARE complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 232 Dm			1 117
+	Rn
		1144061 GOSR1_RAT (3-232): 7.7e-88: 261: 45.12		BET1_RAT (7-117): 1.18e-36: 122: 36.94
+	Hs
		169344 GOSR1_HUMAN (3-232): 9.07e-88: 261: 45.53		BET1_HUMAN (10-117): 1.07e-36: 122: 39.82
+	Rn
		192330 GOSR1_RAT (3-232): 7.7e-88: 261: 45.12		BET1L_RAT (19-114): 1.7e-24: 91.3: 29.90
+	Hs
		309624 GOSR1_HUMAN (3-232): 9.07e-88: 261: 45.53		BET1L_HUMAN (20-114): 3.42e-24: 90.5: 31.25
+	Hs
		212703 GOSR1_HUMAN (3-232): 9.07e-88: 261: 45.53		STX6_HUMAN (8-100): 1.4e-19: 82.4: 22.58
+	Hs
		92385 E9PCW1_HUMAN (3-232): 2.15e-87: 260: 45.49		STX6_HUMAN (8-100): 1.4e-19: 82.4: 22.58
+	Sc
		611775 GOSR1_YEAST (5-228): 3.71e-67: 208: 22.03		BET1_YEAST (17-114): 7.22e-25: 93.2: 21.43
+	Sc
		753358 GOSR1_YEAST (5-228): 3.71e-67: 208: 22.03		SFT1_YEAST (19-116): 2.55e-21: 82.8: 19.39