HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	29176576
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 685
+	Hs
		507895 TRAF2_HUMAN (28-554): 5.57e-103: 321: 31.84		UBC_HUMAN (1-685): 0: 857: 100.00
+	Rn
		92823 D3Z9G0_RAT (2-556): 1.95e-124: 378: 40.74		UBC_RAT (1-637): 0: 779: 98.90
+	Hs
		508892 TRAF6_HUMAN (21-551): 7.73e-81: 264: 22.02		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		507515 RO52_HUMAN (32-468): 7.46e-77: 252: 11.16		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		507902 TRAF1_HUMAN (161-552): 9.41e-75: 245: 29.51		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		508542 TRAF4_HUMAN (29-551): 1.15e-71: 238: 23.32		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		507484 TRI27_HUMAN (32-469): 3.59e-68: 230: 10.97		UBC_HUMAN (1-685): 0: 857: 100.00
+	Rn
		81606 B5DFH7_RAT (28-554): 3.11e-98: 308: 32.03		UBC_RAT (1-637): 0: 779: 98.90
+	Hs
		508670 TRI39_HUMAN (36-468): 1.99e-66: 226: 9.53		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		507891 TRI26_HUMAN (39-383): 1.17e-44: 167: 13.92		UBC_HUMAN (1-685): 0: 857: 100.00
+	Hs
		507966 TRI25_HUMAN (38-387): 1.07e-43: 166: 15.43		UBC_HUMAN (1-685): 0: 857: 100.00
+	Xl
		1274149 NF7B_XENLA (5-483): 8e-66: 226: 10.89		Q7SY79_XENLA (77-685): 0: 752: 99.84
+	Mm
		508938 RO52_MOUSE (31-468): 3e-76: 250: 11.82		UBB_MOUSE (457-685): 1.43e-90: 286: 99.56
+	Hs
		507177 TRAF2_HUMAN (28-554): 5.57e-103: 321: 31.84		UBB_HUMAN (1-77): 1.15e-26: 110: 98.70
+	Hs
		987280 TRAF6_HUMAN (21-551): 7.73e-81: 264: 22.02		RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00
+	Mm
		509100 RO52_MOUSE (31-468): 3e-76: 250: 11.82		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Hs
		507435 TRAF6_HUMAN (21-551): 7.73e-81: 264: 22.02		UBB_HUMAN (1-77): 1.15e-26: 110: 98.70
+	Mm
		509095 TRAF4_MOUSE (29-551): 5.57e-71: 236: 22.95		UBC_MOUSE (1-108): 2.12e-30: 129: 90.74
+	Hs
		507179 TRAF1_HUMAN (161-552): 9.41e-75: 245: 29.51		UBB_HUMAN (1-77): 1.15e-26: 110: 98.70
+	Hs
		507312 TRI11_HUMAN (32-468): 5.66e-74: 244: 12.50		UBB_HUMAN (1-77): 1.15e-26: 110: 98.70