HitPredict

Interactor 1: RORB (Q92753)
Nuclear receptor ROR-beta (Nuclear receptor RZR-beta) (Nuclear receptor subfamily 1 group F member 2) (Retinoid-related orphan receptor-beta)
Gene: RORB

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Hormone_recep~fn3
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 470 Hs			1 735
+	Hs
		1201932 Q58EY0_HUMAN (14-470): 3.32e-134: 396: 100.00		TRIM1_HUMAN (1-735): 0: 599: 100.00
+	Hs
		1134851 NR1D2_HUMAN (15-443): 2.59e-90: 288: 29.94		TRIM1_HUMAN (1-735): 0: 599: 100.00
+	Hs
		1238008 Q6NSM0_HUMAN (18-119): 1.2e-29: 121: 53.40		TRIM1_HUMAN (1-735): 0: 599: 100.00
+	Hs
		879439 NR2C2_HUMAN (4-458): 3.09e-103: 321: 19.67		TRI55_HUMAN (20-400): 1.68e-78: 263: 23.26
+	Hs
		789495 PPARG_HUMAN (5-461): 2.73e-77: 251: 22.34		TRI25_HUMAN (19-706): 1.29e-98: 319: 20.38
+	Hs
		1134837 NR1D2_HUMAN (15-443): 2.59e-90: 288: 29.94		TRI63_HUMAN (19-400): 7.39e-83: 269: 23.71
+	Hs
		1134847 NR1D2_HUMAN (15-443): 2.59e-90: 288: 29.94		TRI55_HUMAN (20-400): 1.68e-78: 263: 23.26
+	Hs
		789548 PPARG_HUMAN (5-461): 2.73e-77: 251: 22.34		TRI63_HUMAN (19-400): 7.39e-83: 269: 23.71
+	Hs
		1244516 Q6PHZ7_HUMAN (4-381): 2.42e-77: 252: 19.02		TRI55_HUMAN (20-400): 1.68e-78: 263: 23.26
+	Hs
		789567 PPARG_HUMAN (5-461): 2.73e-77: 251: 22.34		TRI55_HUMAN (20-400): 1.68e-78: 263: 23.26
+	Hs
		1060623 PPARA_HUMAN (8-461): 9.73e-73: 238: 22.27		TRI63_HUMAN (19-400): 7.39e-83: 269: 23.71
+	Hs
		1060634 PPARA_HUMAN (8-461): 9.73e-73: 238: 22.27		TRI55_HUMAN (20-400): 1.68e-78: 263: 23.26
+	Hs
		520579 RARA_HUMAN (20-95): 1.37e-43: 161: 61.84		TRI25_HUMAN (19-706): 1.29e-98: 319: 20.38
+	Hs
		571980 NR1D2_HUMAN (15-443): 2.59e-90: 288: 29.94		TRI27_HUMAN (16-326): 4.07e-19: 93.2: 15.48
+	Hs
		282920 NR1I2_HUMAN (2-463): 1.19e-81: 261: 22.51		RO52_HUMAN (16-387): 3.14e-22: 102: 11.61
+	Hs
		623320 STF1_HUMAN (15-458): 8.63e-80: 257: 19.91		RO52_HUMAN (16-387): 3.14e-22: 102: 11.61
+	Hs
		571890 PPARG_HUMAN (5-461): 2.73e-77: 251: 22.34		TRI27_HUMAN (16-326): 4.07e-19: 93.2: 15.48
+	Hs
		783186 PPARG_HUMAN (5-461): 2.73e-77: 251: 22.34		TRI23_HUMAN (28-272): 6.44e-17: 86.7: 24.71
+	Hs
		258242 PPARG_HUMAN (5-461): 2.73e-77: 251: 22.34		TRI13_HUMAN (21-117): 1.7e-14: 78.2: 41.24
+	Hs
		572028 Q6NSM0_HUMAN (18-119): 1.2e-29: 121: 53.40		TRI27_HUMAN (16-326): 4.07e-19: 93.2: 15.48