HitPredict

Interactor 1: Q9VJI7 (Q9VJI7)
GEO08441p1 (Like Sm 7, isoform A) (Like Sm 7, isoform B) (Like Sm 7, isoform C) (RH73529p)
Gene: LSm7

Interactor 2: Q9VKW8 (Q9VKW8)
U6 snRNA-associated Sm-like protein LSm4
Gene: CG5356

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	14605208, 20353594
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0000956 - nuclear-transcribed mRNA catabolic process GO:0005688 - U6 snRNP GO:0097526 - spliceosomal tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 110 Dm			1 154
+	Hs
		1356296 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64
+	Dm
		218371 Q9VJI7_DROME (1-110): 5.99e-39: 127: 100.00		SMD3_DROME (2-105): 1.45e-29: 107: 29.81
+	Ce
		1091044 Q23543_CAEEL (10-110): 8.9e-32: 109: 56.44		LSM4_CAEEL (1-82): 8.35e-36: 122: 76.83
+	Hs
		912211 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		LSM4_HUMAN (1-88): 1.03e-40: 134: 88.64
+	Hs
		912752 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73
+	Hs
		912398 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96
+	Hs
		1356292 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		LSM2_HUMAN (1-88): 2.35e-28: 102: 34.78
+	Hs
		911992 LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53		RUXF_HUMAN (3-70): 7.41e-26: 95.5: 33.82
+	Dm
		1097028 Q9VJI7_DROME (1-110): 5.99e-39: 127: 100.00		RUXF_DROME (3-70): 2.59e-18: 76.2: 32.35
+	Dm
		218359 RSMB_DROME (24-95): 1.98e-24: 93.4: 26.03		SMD3_DROME (2-105): 1.45e-29: 107: 29.81
+	Sc
		746327 LSM7_YEAST (2-101): 2.5e-29: 103: 43.14		LSM2_YEAST (1-87): 2.73e-26: 97: 30.77
+	Sc
		767810 LSM7_YEAST (2-101): 2.5e-29: 103: 43.14		LSM4_YEAST (1-82): 3.62e-25: 96.7: 38.04
+	Hs
		912142 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		SMD3_HUMAN (2-105): 3.32e-30: 107: 31.73
+	Hs
		912140 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		SMD1_HUMAN (1-90): 1.1e-29: 106: 27.96
+	Sc
		746307 LSM1_YEAST (3-102): 5.57e-27: 99.2: 25.23		LSM2_YEAST (1-87): 2.73e-26: 97: 30.77
+	Sc
		767790 LSM1_YEAST (3-102): 5.57e-27: 99.2: 25.23		LSM4_YEAST (1-82): 3.62e-25: 96.7: 38.04
+	Hs
		912205 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		LSM2_HUMAN (1-88): 2.35e-28: 102: 34.78
+	Hs
		912173 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		LSM10_HUMAN (3-99): 4.67e-27: 99.7: 25.25
+	Hs
		911791 LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72		RUXF_HUMAN (3-70): 7.41e-26: 95.5: 33.82
+	Hs
		911801 RSMN_HUMAN (24-95): 1.04e-23: 92.7: 27.40		RUXF_HUMAN (3-70): 7.41e-26: 95.5: 33.82